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It relies on their scientific expertise and Prohibited Lists to inform its own policies, ensuring alignment with global anti-doping standards.

Cell 159 , 281294 (2014)

A typical workflow to assess CNS penetration of novel compounds can be to measure the passive permeability using Madin-Darby canine kidney 2 low efflux (MDCKII-LE) transwell assays or parallel artificial membrane permeability assays (PAMPAs), or to determine efflux activity using multi-drug resistance gene 1 MDCK (MDR1-MDCK) or heterogeneous human epithelial colorectal adenocarcinoma (Caco-2) transwell assay 6